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J.Jpn. Surg. Soc.. 82(11): 1346-1353, 1981


Original article

OF BILE ACID MATABOLISM IN PATIENTS AFTER INTESTINAL RESECTIONS

Second Department of Surgery, Yokohama City University School of Medicine (Director: Prof. Shuji Tsuchiya)

Naoki Ishiguro

Bile acid analysis was performed in bile obtained from 33 patients after intestinal resections. Bile acid metabolism and fat absorption were compared according to the extent and site of the intestine resected.
A marked decrease of total bile acid concentration and an increase of G:T ratio were observed after resection of various parts of the intestine. Deoxycholic acid was absent or decreased in these patients except for ones after jejunal resections.
Fat malabsorption was also observed after resections of the intestine except for the jejunum. Although bile acid malabsorption was almost the same, the intensity of the fat malabsorption would vary according to the extent of the ileum resected, and to the presence or absence of terminal ileum and ileocecal valve.
It was concluded that bile acid analysis was important to evaluate the patients after intestinal resections for further follow-up study.


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