J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 4130KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 82(11): 1339-1345, 1981

Original article

HEPATIC CHANGES AFTER DISTAL SPLENORENAL SHUNT AND PORTACAVAL SHUNT (EXPERIMENTAL STUDY)

Second Department of Surgery, Hyogo College of Medicine

Hiroshi Ashida, Nobuyoshi Itoh, Yoshio  Ishikawa, Tokuroh Kusunoki, Masamichi Matsumoto

This study was made to evaluate changes of the liver after performing distal splenorenal shunt in 7 mongrel dogs (shunt dog) and portacaval shunt in 6 mongrel dogs (Eck dog). The following results were obtained.
1) Decrease of local liver blood flow was 13.2% in shunt dogs, whereas it was 47.8% in Eck dogs and this difference was significant (p＜0.01).
2) Decrease of KICG was16.6% in shunt dogs, whereas it was 58.8% in Eck dogs and this difference was also significant (p＜0.01).
3) Ammonia tolerance tests were almost mormal in shunt dogs, wheseas they were abnormal in Eck dogs.
4) Histological changes of the liver were hepatocellular atrophy and degeneration in Eck dogs, whereas almost no changes were observed in shunt dogs.
Thus, splenorenal shunt caused scarcely any disturbance in the liver.

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