J.Jpn. Surg. Soc.. 82(1): 51-68, 1981
Original article
THE EFFECTS OF VASCULAR LIGATION ON GASTRIC BLOOD FLOW AND GASTRIC SECRETION IN DOGS
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Second Department of Surgery, School of Medicine, Yokohama City University (Director: Prof. Shuji Tsuchiya) Toshifumi Ohashi |
Dogs were divided into three groups according to the type of ligation; left gastric arterial ligation; left gastric arterial and left gastroepiploic arterial ligation; and left and right gastric arterial and left and right gastroepiploic arterial ligation. Following the surgical procedure the effects of vascular ligation on gastric blood flow and gastric secretion were determined.
The gastric blood flow and its distribution were determined by the Sr85-microsphere method and heat clearance technique.
After the intravenous infusion of betazole hydrochloride (histimin), gastric juice was collected and free hydrochloric acid was determined by Topfer Michaelis’ method at 10 min. intervals.
1) Betazole hydrochloride induced no significant change in total gastric blood flow, but gave rise to a significant increase in the blood flow of corpus and fundus and a significant decrease in the blood flow of pyloric region.
2) After left and right gastric arterial and left and right gastroepiploic arterial ligation under stimulation with betazole hydrochloride, gastric secretion showed a tran, and gastric blood flow and gastric acid secretion were rapidly returned to pre-ligation level in a short period of time.
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