[Abstract] [Full Text PDF] (in Japanese / 3692KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 81(12): 1552-1558, 1980


Original article

CLINICAL STUDY OF THE ESOPHAGEAL CARCINOMA

*) Second Department of Surgery, Kyushu University, School of Medicine, Fukuoka, Japan
**) Second Department of Surgery, Shimane Medical School, lzumo, Japan

Yasuyuki Okudaira*), Keizo Sugimachi*), Hiroaki Ueo*), Yasunori Natsuda*), Masahito Ikeda*), Kiyoshi lnokuchi*), Teruhisa Nakamura**)

Out of 281 patients with primary carcinoma of the esophagus admitted in the Second Department of Surgery, Kyushu University Hospital, 174 patients (61.9%) underwent subtotal esophagectomy with an operative mortality of 9.2 per cent. The cumulative 5-year survival rate of resected cases was 15.1 per cent. The average survival time of the non-resected cases was 5.3 months. The patients with smal carcinoma, i.e. less than 4 cm in length, had the most favorable prognosis, with their 5-year cumulative survival rate of 37.0 per cent.
Since 1972 we have used active adjuvant therapy involving pre-and postoperative irradiation and postoperative long-term cancer immuno-chemotherapy. When the surgical results were compared between the active therapy and the historical control group in which postoperative radiotherapy was used primarily, the active therapy appeared to be highly effective with statistical significance.


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