J.Jpn. Surg. Soc.. 81(8): 756-765, 1980
Original article
CLINICAL STUDIES ON THE RESECTION PRIMARY HEPATIC CANCERS
|
The First Department of Surgery, Hokkaido University, School of Medicine Yoshinobu Hata, et al. |
1. Resectability for these cancer was 61 %. None of cases survived in the first 10 years, while 2 of 5 cases were expected to cure in the last 10 years.
2. The patients who had high elevation of total bilirubin and GOT 3 days after resection and who had not remarkable elevation of Alkaline-phosphatase or had remarkable elevation of total
3. The histological pattern in which well-differentiated cell component accounted for 50% in volume was expected to cure.
4. Serum α-fetoprotein level per g tumor weight of hepatoblastoma was 0.3 μg/ml in poorlydifferentiated type and 0.04 μg/ml in well-differentiated type.
5. The half-life of serum α-fetoprotein after hepatic resection was less than 2.5 days in patients who were expected to cure and more than 4.6 days in patients who had recurrence.
From these point, the extended hepatic resection and well managed postoperative care will lead to good curability for these tumors. The histological type which is well corelated to prognosis was able to be prospected by the measurement of preoperative serum α-fetoprotein, and the half-life of α-fetoprotein after resection and changes in postoperative liver function were significant for judgement of prognosis.
To read the PDF file you will need Adobe Reader installed on your computer.