J.Jpn. Surg. Soc.. 81(6): 511-526, 1980

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Original article

ANGIOGRAPHIC STUDY ON THE GALL BLADDER DISEASE

Prostaglandin E₁ (PGE1₁ was used to enhance visuality of angiography due to it's own pharmacological vasodelative effect on small vessels.
The peripheral branch of the cystic artery and gall bladder wall were well visualized in cases which showed negative gall bladder figure in the conventional angiography. PGE₁ gave fine angiography enough to magnify two times as to be able to demonstrate the lesion of small artery (50ｰ100μ). By this pharmacoangiographic technique early cancer of gall bladder and minute hepatoma became defectable.
Comparative study was carried out in microangiography between the chronic inflammatory and malignant lesion in the gall bladder region. Deep vascular changes in muscular and serosal layer such as distorty, irregularity of the caliber on the vessels, and neovaseularization were found in the chronic inflammatory diseases.
Important changes in the mucosal and muscular layer such as abnomal vascularization, irregularity of caliber, tapering and abstraction of the vessels were found in the malignant diseases.

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