[
Abstract]
[
Full Text PDF] (in Japanese / 3715KB)
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J.Jpn. Surg. Soc.. 81(6): 505-510, 1980
Original article
PHYSIOLOGIC PULMONARY SHUNT BEFORE AND AFTER SURGICAL TREATMENT OF PORTAL HYPERTENSION
Twenty patients with portal hypertension underwent Sugiura's trans-thoracic esophageal transection with paraesophago-gastric devascularization and splenectomy.
Various physiologic measurements were made before and after the procedure: Room air arterial blood gas, physiologic pulmonary shunt, wedged hepatic vein pressure, and 15' ICG retention.
The following results were obtained:
1. Arterial oxygen tension under 100% oxygen was lower and pulmonary shunt greater in patients with portal hypertension than those of normal control.
2. Arterial oxygens tension and pulmonary shunt under 100% oxygen improved following esophageal transecLion.
It is concluded that the increased pulmonary shunt in portal hypertension patients may primarily be due to the presence of porto-pulmonary shunt and higher closing volume and that other factors may also be in play.
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