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[PDF: Members Only] J.Jpn. Surg. Soc.. 124(5): 431-437, 2023
Feature topic
TREATMENT FOR BREAST CANCER
In breast cancer treatment, the main goal of perioperative systemic therapy is cure, while the main goal of treatment for metastatic breast cancer is palliation of cancer symptoms. In addition, each subtype has distinct risk profiles and treatment strategies. Currently, new drugs such as the cyclin-dependent kinase 4 and 6 inhibitor, antibody–drug conjugation systems, and immune checkpoint inhibitors are being evaluated in breast cancer. Furthermore, some tests such as companion diagnostics and multigene assays are performed to assess suitable prognostic and predictive factors in breast cancer. Therefore, these treatments are diverse and complex. In clinical practice, all recommendations provided by a collaborative multidisciplinary team need to be discussed with patients in a shared decision-making approach. We discuss current approaches and novel strategies for the systemic therapy of breast cancer.
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