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[Members Only] J.Jpn. Surg. Soc.. 120(1): 18-23, 2019
Feature topic
EFFECTIVE INTERVENTION AND FUTURE DEVELOPMENTS FOR THE PREVENTION OF WOUND INFECTION FOLLOWING COLORECTAL SURGERY
The risk for wound infection following colon surgery is high. Wound infections account for 70％ of surgical site infections (SSIs) following colon surgeries. Strategies and evidence for the prevention of wound infection can be extracted from the guidelines for the prevention of SSIs published by the Centers for Disease Control and Prevention in 2017 and from the guidelines published by the World Health Organization in 2016. Effective interventions to prevent wound infection include mechanical bowel preparation along with oral antimicrobials, disinfection of the skin with alcohol-based chlorhexidine gluconate before incision, wound protector devices, perioperative oxygenation, maintaining normal body temperature, antimicrobial-coated sutures, and prophylactic negative-pressure wound therapy. Some of these are evidence-based measures, whereas others are not. Some may not be cost-effective, although others are if high-risk surgical procedures can be adequately identified. These issues should be investigated in the future.
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