J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text HTML] [Full Text PDF] （in Japanese / 262KB） [Members Only]

J.Jpn. Surg. Soc.. 116(2): 99-103, 2015

Feature topic

RECENT ADVANCES IN MEDICAL AND SURGICAL TREATMENT OF ULCERATIVE COLITIS

1) Inflammatory Bowel Disease Center, Yokohama Municipal Hospital, Yokohama, Japan
2) Matsushima Clinic, Yokohama, Japan

Akira Sugita1), Kazutaka Koganei1), Kenji Tatsumi1), Ryo Futatsuki1), Hirosuke Kuroki1), Kyoko Yamada1), Katsuhiko Arai1), Tsuneo Fukushima2)

Recent advances in both medical and surgical treatment of ulcerative colitis have been remarkable. Changes in medical treatment are mainly good results of therapy with the anti-TNF-α antibody, tacrolimus, and those in surgical treatment are an expansion of the surgical indications to include patients with intractable disease, such as treatment refractoriness and chronic corticosteroid dependence, by a better postoperative clinical course after pouch surgery, improred selection of surgical procedures and the timing of surgery in elderly patients. To offer the optimal treatment for patients with ulcerative colitis, new medical therapies should be analyzed from the standpoint of the efficacy and limitations of effect. Long postoperative clinical course of surgical patients including colitic cancer, prevention of postoperative complications should be also analyzed.

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