J.Jpn. Surg. Soc.. 82(3): 277-283, 1981
Original article
EXTRAMURAL VENOUS INVASION AS A PROGNOSTIC FACTOR OF POSTOPERATIVE LIVER METASTASIS IN COLORECTAL CANCER
|
Department of Surgery, Mitsui Memorial Hospital Haruhiko Shida, Takuji Kubo, Masayoshi Sakamoto, Goro Oya |
Venous invasion was recognized in 100 cases (41 %), 44 in only submucosal layer and 56 in extramural space. This incidence was not affected by the location or histological grade of the tumor, but was directly related to the depth of the cancer penetration and the presence of lymphatic metastasis.
Liver metastases were found in 59 cases either during operation or postoperative period. Venous invasion was noted in 69 per cent of this group. Meanwhile 41 cases out of 100 with venous invasion and 31 cases out of 56 with extramural venous invasion showed postoperative liver metastasis.
Curative operation was performed in 175 cases. 93 cases were followed over three years, and 63 per cent of the cases with extramural venous invasion in this group revealed postoperative liver metastasis. There was no significant relationship between lymph node involvement and metachronous liver metastasis.
It is suggested that extramural vein invasion may be valuable in the prognostic evaluation of the colorectal cancer for development of postoperative liver metastasis.
To read the PDF file you will need Adobe Reader installed on your computer.