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J.Jpn. Surg. Soc.. 115(3): 120-124, 2014
Feature topic
NEOADJUVANT CHEMO (CHEMORADIO) THERAPY FOR ADVANCED NON-SMALL CELL LUNG CANCER
Although there has been considerable progress in new-generation cytotoxic agents and radiotherapy techniques, surgery is still one of the best potentially curative therapeutic options for non-small cell lung cancer (NSCLC). For locally advanced NSCLC patients, the recommended treatment is platinum-based chemotherapy or chemoradiotherapy if possible. If surgery becomes feasible after suitable chemoradiotherapy, the long-term survival of such patients is improved. Although the evidence level for induction chemo (chemoradio) therapy is low, the incorporation of chemotherapy, radiotherapy, and surgery will greatly impact the strategy of future lung cancer treatment.
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