J.Jpn. Surg. Soc.. 106(7): 431-436, 2005

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Feature topic

CHILDHOOD RHABDOMYOSARCOMA

Overall five-year survival of Childhood rhabdomyosarcoma (RMS) is reported to be 70％ in the Itergroup Rhabdomyosarcoma Study Group (IRSG), however, the figure in Japan is almost 15％ lower than that of IRSG. Treatment regimen of RMS essentially depends on the histology of the tumor, site, preoperative staging and postoperative grouping that leads to the risk classification. VAC is a standard chemotherapeutic regimen for low and intermediate risk group. Clinical trial with CPT-11 or high dose chemotherapy are underway for high risk RMS.

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