J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 4172KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 103(5): 441-447, 2002

Editorial

ASSESSING LIVER FUNCTION BY MAGNETIC RESONANCE IMAGING TWO-DIMENSIONAL PHASE-SHIFT FLOW MEASUREMENT OF PORTAL VENOUS BLOOD FLOW AFTER ORAL INTAKE OF GLUCOSE

1) Department of Medical Corporation, Tomogikukai Showa Hospital, Fukuoka, Japan
2) Department of Surgery, Showa University Fujigaoka Hospital, Yokohama, Japan

Hidefumi Yagi1), Takemasa Midorikawa2), Michio Sakamoto1), Eiji Masuda1), Mitsuo Saitoh1), Yasuaki Takeyama1), Ei Haku2), Kazuyoshi Ishibashi2), Hiroshi Nemoto2), Hiroaki Kikuchi2), Shoji Sasaya2), Masahiko Yamaguchi2), Yutaka Sanada2), Kaoru Kumada2)

We have already reported that the ratio of portal venous flow 30 min after oral intake of glucose 75 g to that before intake (PVFR30), measured using pulsed-Doppler ultrasonography (US), correlated significantly with other indicators of liver function and that it could be used to estimate hepatic function before surgery, including liver resection1).
In this study, to assess the disadvantages of pulsed-Doppler ultrasonography, PVFR30 was measured using two-dimensional (2D) phase-shift (PS) magnetic resonance imaging (MRI). PVFR30 was measured in 17 patients and 7 volunteers : 13 with liver cirrhosis (LC) and 11 without LC (non-LC).
Portal venous flow could be measured in all patients without any disturbance of intestinal gas or patient fat or the high degree of technical skill that Doppler US requires. PVFR30 was significantly lower in the LC group than in the non-LC group. In addition, it correlated significantly with other indicators of liver function, including the indocyanine green clearance test, prothrombin time, hepaplastin test, and cholinesterase activity.
These results suggest that PVFR30 measured by 2D PS MRI can be used to estimate liver function and that this MRI method can be performed more easily than pulsed-Doppler US.

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