J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 901KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 100(12): 818-821, 1999

Case report

EXPERIENCE OF ORTHOTOPIC LIVER TRANSPLANTATION FROM NON-HEART-BEATING DONORS AT THE UNIVERSITY OF PITTSBURGH MEDICAL CENTER

1) Thomas E. Starzl Transplantation lnsitute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
2) Second Department of Surgery, Hirosaki University School of Medicine, Hirosaki, Japan

Eishi Totsuka1)2), John J. Fung1), Kenichi Hakamada2), Shunji Narumi2), Mutsuo Sasaki2)

Eight cases of orthotopic liver transplantation (OLT) from non-heart-beating donors (NHBDs) were experienced at the University of Pittsburgh Medical Center. Four cases were from donors whose organs were procured following cardiopulmonary resuscitation (uncontrolled NHBD), and the remaining four hepatic allografts were recovered.after sustained cardiopulmonary arrest following extubation in an operationg room (controlled NHBD). After OLT from uncontrolled NHBDS, two allografts failed due to preservation injury and hepatic arterial thrombosis, and one showed poor allograft function. In contrast, all four grafts from controlled NHBDs survived and functioned well worked postoperativery. Hepatic allografts from controlled NHBDS is considered to be useful in OLT, especially in Japan where there is a serious brain-dead donor shortage.

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