J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 2629KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 99(2): 124-128, 1998

Case report

ASYMPTOMATIC PANCREATIC ISLET CELL TUMOR(GLUCAGONOMA)：CASE REPORT

1) Department of Surgery, Yamato City Hospital, Yamato, Japan
2) Department of Pathology, Yamato City Hospital, Yamato, Japan

Akihiko Suto1), Shin Takayama1), Hirotaka Miki1), Hisanao Izumika1), Tatsu-ichiro Tanahashi1), Hiroshi Suzuki1), Toshio Takeshita1), Harumi Ohmiya1), Hiroshi Kijima2)

A case of asymptomatic pancreatic islet cell tumor (glucagonoma) is reported. A 36-year-old woman undergoing a ultrasonic scan was found to have two masses in the body and tail of the pancreas measuring 5 cm and 4cm in diameter, respectively. Investigations of serum peptide hormones revealed an elevated glucagon level of 27,500pg/ml (normal＜100pg/ml), suggesting the possibility of an islet cell tumor (glucagonoma). The patient, however, was asymptomatic although high levels of glucagon were present. The patient underwent distal pancreatectomy to remove the lesions in the body and tail of the pancreas. Histological findings revealed islet cell tumors of the pancreas, and immuno histochemical staining of the tumor cells demonstrated a positive reaction for chromogranin and glucagon.

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