J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 3151KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 97(4): 325-329, 1996

Case report

A CASE OF BRONCHOLO-ALVEOLAR CARCINOMA WITH HIGH PRODUCTION OF CARBOHYDRATE ANTIGEN(CA19-9)

Department of Surgery, Okayama Saiseikai General Hospital, Okayama, Japan

Yasunobu Shioji, Yoshihiro Akazai, Takaomi Takahata, Yasuhisa Okamoto, Tosinori Ohara, Nobumasa Tsutsui, Shuhei Hirose, Kazuo Kataoka

A 75-year-old female had loss of appetite, left hypochondrial and back pain. An X-ray and a computed tomogram of both lungs showed multiple small granular shadows. By Tc-labelled bone scintigram, multiple uptakes were found. Since high serum CA19-9 was obtained, pancreatic or bile duct cancer with multiple lung and bone metastasis was suspected.
The autopsy revealed, small nodules in both lungs were well-differentiated adenocarcinoma, bronchiolo-alveolar type, and immunohistologically, tumor cells were stained positively for CA19-9. Since CA19-9 exists in normal bronchial glands and bronchiole, high level of serum CA19-9 in our patient may be derived from the neoplastic bronchiolar epithelium.

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