[Abstract] [Full Text PDF] (in Japanese / 643KB) [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 96(3): 174-179, 1995


Original article

THERAPEUTIC EFFICACY OF HEPATECTOMY IN THE TREATMENT OF HEPATIC METASTASES FROM BREAST CANCER

Department of Surgery, Cancer Institute Hospital, Tokyo, Japan

Masataka Yoshimoto, Iwao Sugitani, Takuji Iwase, Susumu Watanabe, Fujio Kasumi

This study was performed to evaluate whether or not surgical excision of hepatic metastases from breast cancer has any effect on the prognosis. Between September 1985 and April 1993, eight patients with hepatic metastases (solitary in four cases, multiple in four cases) underwent hepatectomy. Two patients among them had other remote recurrence besides that arising in the liver. Right hepatectomy in two cases, left hepatectomy in one, extended left hepatectomy in one and partial hepatectomy in four were done. No postoperative complications developed. Four patients incurred liver recurrence within an average period of 11.5 months after hepatectomy, with three of average period of 11.5 months after hepatectomy, with three of them dying from the disease within 16 to 36 months after hepatectomy. The other four were free of liver recurrence and remained alive for 3 to 65 months post-operatively. The 50% survival time was 36 months after hepatectomy and 40 months after the discovery of hepatic metastases. Although hepatectomy could only be applied to a restricted number of patients and these results are obviously insufficient, we believe that surgical procedure for liver metastases from breast cancer, if possible, is undoubtedly benefitial in prolonging the survival in such patients.


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