J.Jpn. Surg. Soc.. 93(11): 1410-1415, 1992
Original article
EFFECTIVENESS OF INTRAOPERATIVE CYTOLOGICAL EXAMINATION OF PERITONEAL
WASHINGS FOR PATIENTS WITH PANCREATIC CANCER
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Department of Surgery, National Cancer Center Hospital, Tokyo, Japan Taira Kinoshita, Hideo Ozaki, Tomoo Kosuge, Kazuaki Shimada |
Cytological examination of peritoneal washings or ascitic fiuid at rectovesical pouch or pouch of Douglas was performed in 37 patients with primary pancreatic cancer. Positive results for cancer cells were obtained in five of 9 patients（55.6％）who received cytological examination of ascitic fluid and in seven of 28 patients（25.0％）who received that of peritoneal washings.
Four of 6 patients（66.7％）with visible peritoneal dissemination showed positive results. These 6 patients died of peritoneal dissemination with about 10 months.
Eight of 31 patients（25.8％）without visible peritoneal dissemination showed positive results of the cytological examination. Two of the 8 patients received resection of the tumor. Other 6 patients without resection developed clinically evident peritoneal carcinmatosis.
A high positive rate（66.7％）of cytological examination of the patients with visible peritoneal dissemination and a high incidence of appearance of peritoneal carcinomatosis in patients with positive cytological results but without visible peritoneal dissemination（75.0％; positive vs 26.1％; negative）indicate a high reliability of the cytological examination to detect invisible micro-peritoneal dissemination.
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