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J.Jpn. Surg. Soc.. 93(9): 1100-1103, 1992


Report on the annual meeting

THERAPEUTIC VALUE OF HEPATECTOMY AND TRANSCATHETER ARTERIAL EMBOLIZATION (TAE) FOR HEPATOCELLULAR CARCINOMA

Department of Surgery I, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan

Shigeaki Takeda, Hideto Tashiro, Hiromi Koho, Yuji Abe, Yukihisa Nagafuchi, Kohji Okamoto, Keiichi Ohsato

Therapeutic value of hepatectomy and T AE was evaluated retrospectively in 150 hepatectomized and 117 non-hepatectomized patients of hepatocellular carcinoma (HCC). Operative death was seen in 5 patients. Cumulative 5 years survival rate and disease free cumulative 5 years survival rate of the 145 hepatectomized patients were 35.4 per cent and 23.6 per cent respectively. These survival rates were significantly affected by tumor size, intrahehatic metastasis (IM) and vascular invasion (Vp). But the influences of tumor margin (TW) and curative resection (relativec urative or relative non-curative) were slight. Ninety-two patients (69 : dead, 23 : alive) had tumor recurrences. TAE was performed in 56 out of 92 patients effectively and 2 years survival rate was 31.5 per cent.
Overall cumulative 5 years survival rate of non-hepatectomized patients was 6.6 per cent, but this group showed a more reduced hepatic reserve and more advanced tumor stage. Six patients treated by TAE survived more than 4 years.
Hepatectomy is a first option for the treatment of HCC since complete cure may be estimated. However, because of operative risk and higher recurrence rate, use of current multidiciplinary treatment including TAE is necessary for the prognostic improvement of HCC with or without hepatectomy.


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