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J.Jpn. Surg. Soc.. 93(9): 1055-1058, 1992


Report on the annual meeting

THE TREATMENT OF CHOICE IN DEEP VEIN THROMBOSIS OF THE LOWER EXTREMITY

1) The First Department of Surgery, Nagoya University School of Medicine, Nagoya, Japan
2) The First Department of Internal Medicine, Nagoya University School of Medicine, Nagoya, Japan

Tsunehisa Sakurai1), Atsuhiko Maki1), Naomichi Nishikimi1), Teruo Ikezawa1), Takashi Yano1), Junki Takamatsu2), Kazuo Kagami2)

Of 67 patients with actue deep vein thrombosis of the lower extremity (DVT), 43 patients were treated by venous thrombectomy and 24 patients were managed by conservative treatment. The clinical effect of thrombectomy was evaluated by analyzing follow-up results in the 2 groups. The cumulative incidences of pigmentation and stasis ulcer at the 5th year were 2.7% and 0% respectively in the thrombectomy group, and 24.3% and 10% respectively in the conservative treatment group. Pigmentation and stasis ulcer were significantly more frequent in the conservative treatment group (p<0.01). It is concluded that venous thrombectomy is superior to conservative treatment to prevent late postthrombotic sequelae.
Protein C, protein S and plasminogen were assayed in 40 DVT patients to determine the incidence of hypercoagulable state in DVT. Congenital deficiency or abnormality were found in 15 patients (37.5%). In such DVT patients with thrombophilia anticoagulant prophylaxis should be continued to decrease a risk of rethrombosis.


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