J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 2222KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 93(9): 918-921, 1992

Report on the annual meeting

EARLY DIAGNOSIS AND MANAGEMENT AGAINST PERIOPERATIVE FUNGUS INFECTION

1) Department of Surgery, Kariya General Hospital, Kariya, Japan
2) The First Department of Surgery, School of Medicine, Nagoya City University, Nagoya, Japan

Takashi Okubo1), Shizuo Usami1), Yasuhiro Kamiya1), Yasushi Takeuchi1), Hikozo Kotani1), Nagao Shinagawa2), Jiro Yura2)

Candida spp. is frequently detected from perioperative patients, especially from those requiring central venous catheter (CVC) management. CAND-TEC could detect the blood fungus infection easily and quickly. We analyzed 438 specimens from 57 patients requiring perioperative CVC management for more than three weeks, and investigated usefulness of CAND-TEC comparing with other serological methods.
The dilution rate of CAND-TEC showed a positive correlation with amount of β-D-glucan which was measured by Toxicolor test and Endotoxin-specific assay. It also showed a positive correlation with amount of D-arabinitol. When blood samples diluted more than four times were positive with CAND-TEC, the patients were considered to be infected, and accumulative infection rate was up to 84.2％ three weeks after introduction of CVC management.
CAND-TEC would be useful in detecting Candida infection compared with conventional methods, and the fungus infection was much more frequent incidence than ever expected. It is important to detect fungus infection early and respond immediately to avoid nosocomial infection.

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