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Abstract]
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Full Text PDF] （in Japanese / 1579KB）
[Members Only And Two Factor Auth.] J.Jpn. Surg. Soc.. 93(9): 895-897, 1992
Report on the annual meeting
POSTOPERATIVE INFECTION WITH METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AND ITS CONTROL MEASURES IN PATIENTS WITH ESOPHAGEAL CANCER
－PREDICTION OF HIGH RISK PATIENTS－
Whether or not compromized host defense prior to surgical treatment is related to development of infection with methicilin-resistant staphylococcus aureus (MRSA) following major surgery was examined. Of 22 patients undergoing esophagectomy for cancer between 1989 and 1990, 5 were free from MRSA colonization and infection (group I) while 8 had MRSA colonization without infection (group II) and 9 had MRSA infection (group lll). Levels of neutrophil citocydal functions, complements, immunoglobulins and cell-mediated immunity were not significanty different among these three groups. The mean of anti pneumococcal polysaccharide (PPS)-IgG was significantly lower in group III than in group I (p＜0.05) and tended to be lower than in group II (P＝0.08). All infected patients showed a titer＜600 EU while all but one non-infected patient did so＞600 EU. Serum IgG2 levels positively correlated with anti-PSS IgG levels. Thus, we concluded that a preoperative evaluation of antibody response against polysaccharides and serum IgG2 levels can serve to predict development of MRSA-related infection following esophageal surgery.
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