J.Jpn. Surg. Soc.. 92(9): 1074-1077, 1991
Report on the annual meeting
THE GROWTH RATE AS A PARAMETER OF DEGREE OF BIOLOGICAL MALIGNANCY AND PREDICTION OF METASTASIS BY TUMOR MARKER DOUBLING TIME AND HALF TIME
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1) Department of Surgery, Cancer Research Institute, Kanazawa University, Kanazawa, Japan Yutaka Takahashi1), Masayoshi Mai1), Satoru Kasama2) |
Tumor marker doubling time of liver metastasis (28.4±11.5 days) in 32 cases was significantly shorter from that of lymph node metastasis (42.3±21.4 days) in 18 cases and of peritonitis carcinomatosa (41.1±25.8 days) in 21 cases. These result indicate that the tumor marker doubling time will be able to play a role in prediction of recurrent patterns.
Tumor marker half time after operation ranged from 4 to 5 days in all cases without recurrence, while the discrepancy from actual half time was observed in cases with metachronous liver metastasis diagnosed within 6 months. These results suggest that the discrepancy from actual half time of tumor marker after operation indicates the latent cancer cells and this plays a role in prediction of metachronous liver metastasis.
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