J.Jpn. Surg. Soc.. 91(9): 1434-1437, 1990
Report on the annual meeting
EVALUATION OF MYOCARDIAL PROTECTION DURING A-C BYPASS SURGERY BY RETROGRADE CARDIOPLEGIA（cp）
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Department of Thoracic Surgery, Nippon Medical School, Tokyo, Japan Shigeo Tanaka, Ryuzo Bessho, Shinichi Osaka, Junichi Ninomiya, Masatoshi Ikeshita, Teruo Takano*), Tasuku Shoji |
From 1980 to 1988, we had 143 cases of CABG, and PMI rate was 13 to 15%. Since 1989, myocardial protection method has been changed from conventional antegrade (CP) alone to the combination of retrograde CP with the antegrade CP.
Only ope case (3.3%) of 30 consecutive A-C bypass surgery for three vessel disease showed the complication of PMI.
These results demonstrated that the retrograde CP may be effective to prevent the ischemic injury in site of stenotic coronary artery.
However, the obtained value of lactate, hypoxanthine and xanthine just after the aortic declamping showed the existence of moderate ischemic and reperfusion injury. Therefore, these data suggested the importance of additional myocardial protective means such as terminal blood cardioplegia as well as free radical scavenger.
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