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J.Jpn. Surg. Soc.. 91(9): 1430-1433, 1990


Report on the annual meeting

COMBINED METHOD OF ANTI- AND RETROGRADE PERFUSION OF CARDIOPLEGIA

Division of Cardiovascular Surgery, Institute of Angiocardiology, Kyushu University, Fukuoka, Japan

Kazuhiko Kinoshita, Masato Sakamoto, Munetaka Masuda, Hisanori Mayumi, Toshihide Aso, Koji Matsuzaki, Yoshito Kawachi, Koichi Tokunaga

We have experimentally reported usefulness of the combined method of anti- and retrograde perfusion of cardioplegic solution in cases with coronary artery stenosis. In the present study, we have compared myocardial protective effect of this combined method (Retro-group, n=13) and antegrade perufison method alone (Ante-group, n=14) in patients who underwent coronary artery bypass gafting (CABG). Postopeative recoveries of cardiac function and rhythm and postoperative values of serum CK-MB and myoglobin were similar in the two groups. Additionally patients who underwent CABG to LAD using internal thoracic artery (ITA) in each group were selected and compared (Ante- and Retro-subgroup, n=6 in each). Postoperative cardiac index was singnificantly higher in Retro-subgruup (< 0.02) although there were no differences in CK-MB and myoglobin. Thus, the combined method of anti-and retrograde cardioplegia can afford optimal myocardial protection especially in patients in whom ITA is used.


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