J.Jpn. Surg. Soc.. 91(9): 1280-1282, 1990

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Report on the annual meeting

TREATMENT OF CHOLELITHIASIS －COMPARISON OF ESWL WITH SURGERY FOR GALLBLADDER STONE－

Cholecystectomy was performed for 712 patients with cholecystolithiasis. Over-all, the morbidity rate was 5.9 per cent and included residual stone in two, bile peritonitis in three, and hemobilia in one. Two patients died of systemic complications after surgery. Eighty-eight patients were treated with GM-1, MPL9000, and Therasonic lithotripter. Twenty-seven per cent of these patients were free from gallstone after ESWL. Complications including skin petechiae and microscopic hematuria as a result of energy/trauma of ESWL were relatively minor and usually transient. The experimental study showed, however, the massive bleeding in the gallbladder and liver just after the shock wave exposures. To evaluate the efficacy of gallstone dissolution therapy after ESWL, 27 patients were randomized to receive either ESWL plus UDCA (600mg) and CDCD (100mg) or ESWL plus placebo. Our results did not clarify whether there is any advantage to the use of ESWL plus UDCA and CDCA as opposed to ESWL alone.

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