J.Jpn. Surg. Soc.. 91(9): 1231-1233, 1990

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Report on the annual meeting

EXTENSIVE SURGERY FOR HEPATOCELLULAR CARCINOMA（HCC）
－SIGNIFICANCE AND ISSUES－

In order to increase the resectability and curability of HCC, we have been treating HCC by means of extensive surgery supported by the Redox Theory, which can be used to evaluate the liver function in the perioperative period.
Extended resection including the surrounding tumor free parenchyma has contributed to the longer survival of patients with small HCCs. Resection of the tumor-bearing segment plus one additional segment were performed in 14 cases with 100% of 5 year cumurative survival.
Survival of patients with advanced HCCs, particularly when accompanied with tumor thrombi in the confluence of the portal vein is very short. Since the introduction of metabolic intensive care based on the Redox Theory, aggressive surgical resection has been applied to those patient groups in addition to other multimodality treatments. The 3 year survival of 21% in this group is comparable to the 4 year survival of 20.4% in the case of liver transplantation for hepatic malignancy.

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