J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 1820KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 90(9): 1389-1391, 1989

Report on the annual meeting

TREATMENT OF LYMPHANGIOMAS ARISING AROUND CERVICO-FACIAL REGION : SURGERY, BLEOMYCIN THERAPY AND OK-432 THERAPY

Division of Surgery, Children’s Research Hospital Kyoto Prefectural University of Medicine, Kyoto, Japan

Shuhei Ogita, Toshiaki Tsuto, Ei-ichi Deguchi, Kazuaki Tokiwa, Jun Yanagihara, Naomi Iwai

To determine a favorable treatment for lymphangiomas arising around cervico-facial region, a 10-year (1979, 1ｰ1988, 9) experience with 58 these lesins were reviewed. Therapeutic records were divided into 3 groups according to the treatment : surgical Excision (n＝16), intralesional Bleomycin (BLM) therapy (n＝11), and intralesinal OK-432 PicibanilⓇ therapy (n＝31) .
Complete disappearance of the lesions without serious complications was noted in 3 of 16 patients treated by surgery, in 3 of 11 patients treated by BLM therapy, and in 21 of 31 patients treated by OK-432 therapy. Serious complications such as facial nerve palsy (3), ugly scars due to repeated excision (5) and short of tounge (1) were noted in surgically treated group. In BLM and OK-432 therapy groups, only a fever of 2 to 3 days’ duration and local inflammatory reaction of 3 to 5 days were noted. The results suggest that OK-432 therapy is effective for these lesions.

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