J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 710KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 89(9): 1430-1432, 1988

Report on the annual meeting

DIURNAL PROFILE OF GASTROINTESTINAL HORMONES IN POSTPAN－
CREATECTOMIZED STATE

First Department of Surgery, Faculty of Medicine, Kyoto University, Kyoto, Japan

Tadao Manabe, Noboru Asano, Kenichiro Yamaki, Tetsuya Hirano, Atsushi Nonaka, Nobuo Baba, Takayoshi Tobe

A long-term follow-up study revealed that diabetes, diarrhea and dumping syndrome were the major complications after pancreaticoduodenectomy. The PABA recovery rate in PFD test was markedly decreased in patients with pancreaticoduodenectomy, suggesting that impaired exocrine pancreatic function is the main cause of the complications. A 24-hour profile of pancreatic juice secretion more than 1.5 months after operation, showed that pancreatic juice was rich in protein and amylase, and secretion was increased following a meal and early in the morning. Gastrin, CCK and VIP were not detected during these periods ; however, secretin and motilin were increased. These results suggest that pancreatic exocrine function recovered in patients with pancreaticoduodenectomy and secretin and motilin played an important role in the regulation of these functions.

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