J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 1723KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 89(9): 1355-1358, 1988

Report on the annual meeting

NUTRITIONAL SUPPORT IN CRITICALLY ILL PATIENTS; WITH
SPECIAL REFERENCE TO FAT EMULSION AND CARNITINE

Third Department of Surgery, Facuity of Medicine, Tokyo University, Tokyo, Japan

Mitsuru Yamakawa, Jun Maeda, Yoshikazu Mimura, Toyoki Fujita, Katsuyoshi Sugisaki, Kiyokazu Furuya, Takeshi Oohara

Energy metabolism of fat emulsion was studied in rats with septic conditin. The results indicate that fat emulsion was rapidly eliminated from the blood stream and metabolized readily even in such condition. Based on these findings, we have actively employed fat emulsion clinically as an energy source of septic patients.
In septic rats, it was demonstrated that levels of carnitine decreased and that this decrease was based upon a decrease of synthesis. When carnitine was administered together with fat emulsion， the energy metabolism returned to approximately nomlal level.
This reports also describes the absorption and utilization of orally administered fat in septic rats.

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