J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 362KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 89(5): 641-645, 1988

Original article

THE CORRELATION BETWEEN REDUCTION RATE OF TUMOR AND SUR-
VIVAL TIME OF PATIENT AS AN EFFECT OF CHEMOTHERAPY

Department of Surgery, Cancer Research Institute, Kanazawa University, Kanazawa, Japan
*) Toyosu Hospital, Showa University, School of Medicine, Tokyo, Japan

Yutaka Takahashi, Satoru Kusama*), Masayoshi Mai

The correlation between reduction rate of tumor by anti-cancer chemotherapy and survival time of patients was studied in 17 cases with liver metastases from 12 stomach cancers and 5 colonic cancers. The survival time ranged from 4 to 15 months (mean 8.4±4.3months) in 5 cases with CR or PR, from 6 to 15 months (mean 9.8±4.1 months) in 4 cases with NC, from 2 to 12 months (mean 8.0±3.7months) in 8 cases with PD. There was no correlation between reduction rate of tumor and survival time ofpatients.
The tumor marker doubling times, both before and after chemotherapy, were studied in 5 cases. The difference of doubling time between before and after chemotherapy was not significant.
These results suggest that individual doubling time plays an important role in survival time as an effect of chemotherapy.

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