J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 2011KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 86(9): 1157-1160, 1985

Report on the annual meeting

G-I HORMONES AND GASTRIC FUNCTIONS
ーWITH SPECIAL REFERENCE TO THE PYLOROPLASTY FOR THE SELECTIVE PROXIMAL VAGOTOMYー

Second Department of Surgery, Jikei University School of Medicine, Tokyo, Japan

Nobuyoshi Hanyu, Teruaki Aoki, Sumio Takayama, Kimiyuki Tokuyasu, Yoshiyuki Furukawa, Yoichi Ohira, Fusahiro Nagao

Serum gastrin changes before and after selective proximal vagotomy (SPV) were studied in relation to the gastric motility and the acid secretion clinically and experimentally and the effects of pyloroplasty were investigated.
Results and conclusions :
1. Experimental studies revealed that test meals provoked gastrin secretion to stimulate gastric motility. Periodical gastric acid secretions were observed during hunger period, along with elevated serum gastrin levels. After SPV, gastrin responces to the test meals were significantly increased so that the pyloric ring motility was disturbed.
2. Clinical studies revealed that adrenalin infusion test provoked significant gastrin responces to secrete acid secretions in duodenal ulcer patients. After SPV, increased gastrin responces to adrenalin restored acid secretions as much as preoperative acid secretions responded to the adrenalin test.
Pyloroplasty for the SPV inhibited the gastrin and acid secretions responded to the adrenalin test.

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