J.Jpn. Surg. Soc.. 86(6): 738-751, 1985
Original article
SYSTEMIC HEMODYNAMICS AND OXYGEN METABOLISM IN ACUTE PORTAL VEIN OCCLUSION AND FOLLOWING RESTORATION OF PORTAL VEIN FLOW IN CANINES
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The Second Department of Surgery, Nagoya University School of Medicine, Nagoya, Japan Sumito Hoshino, Toshiaki Nonami |
Acute abnormality was observed on systemic circulation and oxygen metabolism quickly after PVO, causing the shock to dogs. The hypovolemia causing by splanchnic sequestration was the leading cause at the early stage. As the occlusion time was extended, the cardiac function was lowered and the oxygen metabolism was destroyed. Using AnthronⓇ bypass catheter between portal and femoral veins during the PVO, the intestinal blood congestion was prevented and the influence on the oxygen metabolism was slight.
After R-PVF, the cardiac functional deterioration and deficient compensation of oxygen metabolism were observed, which were more worsed as the occlusion time was longer. The simultaneous occlusion of the portal vein and superior mesenteric artery failed to improve the deterioration of systemic circulation and oxygen metabolism. No improvement of prognosis of dogs was found either. On the contrary, the systemic circulation was improved through the administration of dobutamine during PVO and after R-PVF, the improvement of systemic circulation and oxygen metabolism was also improved and the prognosis of dogs was improved.
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