J.Jpn. Surg. Soc.. 86(6): 657-668, 1985
Original article
CLINICAL SIGNIFICANCE OF URINARY N-ACETYL-β-D-GLUCOSAMINIDASE ACTIVITIES IN SURGERY
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First Department of Surgery, Fukushima Medical School, Fukushima, Japan Toshio Kamioka |
1) The preoperative U-NAG activities were 9.53±8.63IU/day in patients in elective operations, and 31.39±23.47 IU/day in cases in emergency surgery or exploratory laparotomies.
2) The U-NAG activities were elevated slightly even in patients with no postoperative complications, suggesting there was significant damage to the renal tubular epithelium.
3) In the patients with postoperative complications, the U-NAG activities were elevated markeldy, especially in those with circulatory shock, suggesting severe damage to the renal tubular epithelium.
4) Though the U-NAG showed abnormally high activities. the values of BUN, S-Cr, U-protein, UUN/BUN, FENa, Ccr, CH2O remained within the normal range. On the contrary, when they were abnormal, the U-N AG activities were not elevated.
5) All patients, who showed high U-NAG activities with abnormal values of Ccr and/or CH2O, developed acute renal failure (ARF). In order to detect ARF in an early stage, Ccr and CH2O should be measured when U-NAG activities rose to over 50 IU/day.
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