J.Jpn. Surg. Soc.. 85(11): 1472-1478, 1984
Original article
EXPERIMENTAL STUDY ON QUANTITATIVE EVALUATION OF FATTY LIVER BY COMPJTED TOMOGRAPHY
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Second Department of Surgery, Gifu University School of Medicine, Gifu, Japan Tokuro Kunieda, Ryo Kawata, Koki Nayashi, Tsutomu Nishiwaki, Katsuyuki Kunieda, Shigetoyo Saji, Kazuki Sakata |
In 2 groups of rabbits, in which 2g/kg/day and 4g/kg/day of fat emulsion were adminstered intravenously for 4 weeks respectively, post-treatment reduction in CT value of light dergree was observed. In a group, in which 8g/kg/day were given, there was a sufficient reduction in CT value for giving diagnosis of fatty liver of moderate degree.
Significant correlation was found between changes in CT value of the liver on the one hand and contents of triglyceride, total cholesterol and cholesterol ester in the liver on the other hand, while there was no significant correlation between changes in CT value and contents of phospholipid, protein and water.
Significcant correlation was found between changes in CT value of the liver and degress of histological fat accumulation in the liver cells.
It has been evidenced experimentally that prolonged administration of fat emulsion may cause fatty liver, and that measurement of CT values of the liver is a non-aggressive method of diagnosing fatty liver.
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