J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 2909KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 85(9): 1114-1118, 1984

Report on the annual meeting

PATHOLOGICAL STUDY OF HEPATOLITHIASIS WITH SPECIAL EMPHNSIS ON UNUSUAL CASES

1) Second Dept. of Path., Kanazawa Univ., Kanazawa, Japan
2) First Dept. of Surgery, Kyushu Univ., Fukuoka, Japan
3) Second Dept. of Surgery, Nagasaki Univ., Nagasaki, Japan
4) Second Dept. of surgery, Hirosaki Univ., Hirosaki, Japan
5) Dept. of Path., Fukui Prefectural Hosp., Fukui, Japan
6) Digest. Drpt. Tokyo Women Med. College, Tokyo, Japan
7) First Dept. of Surgery, Tohoku Univ., Sendai, Japan
8) First Dept. of Surgery, Nihon Med. College, Tokyo, Japan
9) Second Dept. of Surgery, Kanazawa Univ., Kanazawa, Japan
10) First Dept of Surgery, Mie Univ., Tsu, Japan

Y. Nakanuma7), G. Ohta7), K. Yamaguchi2), A. Koga2), K. Yamamoto3), M. Sasaki4), K. Doishita5), T. Yoshikawa6), F. Hanyu6), W. Takahashi7), Y. Moriyama8), T. Nagakawa9), Y. Ogura10), R. Mizumoto10)

Morphological survey was performed in 140 liver specimens of hepatolithiasis which were collected from several pathological and surgical Departments in Japan. Among them there were 19 cases with unusual features suggestive of presumed lithogenetic processes. They consisted of association of congenital dilatation of biliary tree (5 cases), association of stenosis or obstruction of biliary tree occurring prior to lithiasis. (4 cases), association of anomalous communication between biliary tree (1 case), presence of serous glands simulating to pancreatic exocrine glands in biliary tree (1 case), association of non-biliary hepatic cirrhosis (4 cases), association of chronic ulcerative colitis (1 case), intrahepatic cholesterol stone (2 cases) and association of granulomatous cholangitis (1 case). Chronic proliferative cholangitis which is consistently seen in a common type of hepatolithiasis was found in about a half of these unusual cases and not in the remaining cases. Based on the observations of these unusual cases, the following suggestions were obtained : 1. dilatation, bile stasis or cholangitis may be a lithogenic factor of hepatolithiasis, and 2. chronic proliferative cholangitis associated with a numerous amount of mucinous glands is not always a prerequisite lesion and exerts a promoting and accelerating effect in hepatolithiasis.

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