J.Jpn. Surg. Soc.
ISSN 1880-1129

[Abstract] [Full Text PDF] （in Japanese / 2791KB） [Members Only And Two Factor Auth.]

J.Jpn. Surg. Soc.. 85(1): 77-81, 1984

Original article

A CASE OF α-FETOPROTEIN-PRODUCING GASTRIC CARCINOMA WITH UNIQUE MACROSCOPICAL CONFIGURATION

Second Department of Surgery, Faculty of Medicine, Unversity of Tokyo, Tokyo, Japan
*) Department of Pathology, Faculty of Medicine, Unversity of Tokyo, Tokyo, Japan

Takaya Kodama, Kazuo Shibayama, Fukuei Kanai, Ichiro Iizuka, Mamoru Hiraishi, Youichi Tanaka, Tatsuhiko Takahama, Kenji Katayama, Yuuji Maruyama, Tatsuo Wada, Shuuji Takahashi*), Kazuo Nagashima*)

A gastric carcinoma with unique macroscopical configuration was resected from a 63-year-old male patient. Serum level of α-fetoprotein (AFP) was markedly elevated (19,000 ng/ml), and AFP-positive cells were found in the carcinomatous tissues. The cytoplasm of the carcinoma cells appeared to be watery-clear by light microscopy, however, electron microscopy revealed abundant amorphous substances in their cytoplasmic matrix. The unique macroscopical configuration of the gastric carcinoma may reflect its biological resemblance to hepatocellular carcinoma. Such a case may be rare, but AFP production, per se, seems to be a rather universal phenomenon of gastric carcinomas.

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