J.Jpn. Surg. Soc.. 84(1): 20-30, 1983

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Original article

RENAL FUNCTION AFTER NON-BLOOD PRIMING EXTRACORPOREAL CIRCULATION

Non-blood priming extracorporeal circulation (ECC) in open heart surgery was studied to evaluate its effect on kidney, and was compared with blood-priming ECC. Non-blood priming ECC was performed in 49 cases, and blood-priming ECC was performed in 25 cases. Serum creatinine, creatinine clearance, BUN, UUN /BUN and urinary Na/K ratio were measured.
Perfusion flow, total peripheral vascular resistance (TPR) and cardiac index after ECC were measured to know if there is a significant difference between the two groups.
The following results were obtained:
i) There were no significant differences between the two groups as to the perfusion flow, TPR during ECC and cardiac index after ECC.
ii) Using non-blood priming ECC was found to be the safer method from the point of preserving the renal function.
iii) When compared with blood priming ECC, the non-blood priming ECC was found to be more beneficial for the renal function.
iv) Renal failure was observed in 3 pediatric cases using blood priming ECC and 1 adult case using non-blood priming ECC. Low cardiac output syndrome or heart failure were thought to be causes of the renal failure in these 4 patients.

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