J.Jpn. Surg. Soc.. 83(9): 1113-1117, 1982
Report on the annual meeting
RECENT ADVANCES IN MANAGEMENTS FOR MULTIPLE ORGAN FAILURE (MOF) FOLLOWING GASTROINTESTINAL SURGERY
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The Second Department of Surgery, Osaka University Medical School, Osaka, Japan Yoshitaka Ogawa, Takahiko Hara, Junichi Kambayashi, Tokuhiro Miyamoto, Satoshi Tane, Yoshihiro Kido, Sadamasa Takahashi, Takeo Fujiyama, Katsuhiro Kawasaki, Kazuhiro Okagawa, Nobuyuki Taenaka*), Yasuhiro Shimada*), Goro Kosaki |
In the first four years, 26 of the 29 patients developed DIC and only 14 patients were recovered. In the last two years, 4 patients were prevented from DIC and 7 of 8 patients with DIC were recovered from it by the administration of heparin and/or gabexate mesilate (FOY). However, the improvement of DIC did not always coincide with the final outcomes of patients. Organ failures were improved only in the cases whose infectious focuses were controlled successfully. Most of the patients for the first four years had the delayed drainages under the local anaesthesia but 7 of the 9 patients with abdominal infections in the last two years were successfully controlled by the four proper and early drainages and three exploratory laparotomies under general anaesthesia.
The treatment of DIC by FOY and heparin and the aggressive surgical approach for the control of infectious focuses were considered to contribute to the decreased mortality of MOF patients in the recent two years.
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