J.Jpn. Surg. Soc.. 83(9): 1108-1112, 1982
Report on the annual meeting
CLINICAL STUDIES ON MULTIPLE ORGAN FAILURE IN GASTROENTEROGICAL SURGERY
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First Department of Surgery, Tottori University, School of Medicine, Yonago, Japan Okitsugu Nishimura, Toshinari Odachi, Haruaki Ogawa, Tsutomu Takeuchi, Tohru Hinohara, Kiyoshi Kishi, Masakatsu Inoue, Shigemasa Koga |
The incidence of MOF (two or more) was 2.7%, and thirty-three of the 37 patients died giving a high mortality 89%. Among these 37 patients, twenty-five (67%) had various predisposing factors to MOF preoperatively, such as marked anemia, poor nutrition, systemic disease, infection and/or organ disorder.
In thirty of the patients (81%), severe intra-abdominal infections or sepsis were associated with MOF during post-operative course. And majority of the onset of MOF was related to these severe infections as a main causative factor, especially remarked in respiratory failure or gastrointestinal bleeding.
The incidence of organ failure was highly observed in pulmonary, gastrointestinal, liver and renal systems, but correlation with the onset of each failure was variable and could not be enough clarified.
In many cases, reoperative drainage and aggressive support or medication were applied. However, they were ineffective with a fatal outcome despite the considerable efforts.
Therefore, it should be stressed for prevention of organ failure that better control of surgical infections is the most essential and an application of surgical drainage for the intra-abdominal infections should be performed timely in early stage under carefull postoperative managements.
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