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J.Jpn. Surg. Soc.. 83(9): 1104-1107, 1982


Report on the annual meeting

TREATMENT IN ELDERLY PATIENTS WITH GASTRIC CANCER

Department of Surgery, Research Institute for Nuclear Medicine and Biology, Hiroshima University, Hiroshima, Japan

Minoru Niimoto, Masashi Hirono, Kazuhiko Nakagami, Toshihiro Hirai, Yoshihiro Nosoh, Ken Yoshinaka, Mitsutoshi Oride, Tetsuya Toge, Takao Hattori

During the period from Jun. 1973 to Dec. 1980, 607 patients of gastric cancer were operated by total or proximal gastrectomy with complete removal of group 1 and 2 lymph nodes. Of the 607 patients, 145 were in elderly patients who were over 70 years old group. Operative mortality refers to death within thirty days after surgery was 5.5% in elderly group compared with 2.3% in the group below 69 years old. Adjuvant immunochemotherapy was performed, but the cases of intramucosal early cancer were excluded. Massive dose of Mitomycin-C was routinely administered ; 20mg on the day of gastrectomy and another 10mg on the next day, intravenously. The additional 10mg was not given to those older than 70 years old and those having been gastrectomized totally with combined resection of the liver, pancreas or transverse colon. Corrected survival rate of the elder patients were not significantly different from that of the group of younger 69. The reactivity of the lymphocyte responsiveness to PHA was reduced according to the stage of the disease, but in each stage significant difference was not found between the group of younger 69 and older 70. In elderly patients if the treatment was performed on the basis of strict indication, it is clear that the result is comparable to that in younger patients.


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