J.Jpn. Surg. Soc.. 83(9): 891-895, 1982
Report on the annual meeting
EVALUATION OF THE COMBINATION THERAPY FOR THE CANCER OF THE ESOPHAGUS
|
Second Department of Surgery, Osaka University Medical School, Osaka, Japan Kazuhiro Okagawa, Yoshitaka Ogawa, Sumio Mizunoya, Michio Ogawa, Katsuhiro Kawasaki, Yoshihiro Kido, Hitoshi Shiozaki, Jiro Fujimoto, Takeshi Terashima, Song-Jin Han, Kazuhisa Ueno, Kenji Kobayashi, Goro Kosaki |
Materials and methods :
A total of 182 patients with esophageal cancer was resected at the Second Department of Surgery, Osaka University Hospital, in the period from Jan. 1969 to Dec.1980. We devided these patients into groups according to the classification of the combination therapy they received : 1) pre and/or postoperative radiation group and 2) postoperative bleomycin group. The cumulative survival rate of these groups and the multivariable analysis of the factors influenced on the survival such as lymphnode metastasis, adventitia invasion and lymphatic invasion, were investigated.
Results:
1) The preoperative radiation therapy showed no effect on the survival rate in the cases with a3 or ly(+). 2) The postoperative radiation therapy improved the 1-year survival rate. A long-term survival could be expected even in the absolute non-curative patient when preoperative radiation or postoperative bleomycin therapy was added. 3)The postoperative bleomycin was expected to improve the survival rate when the curative resection was performed. This therapy was especially effective in the case with ly(+). In contrast,the bleomycin therapy showed no effect on the n≧3 cases. 4) The postoperative bleomycin therapy was more effective on the survival of the tumor type or scirrhous invasion type of esophageal cancer than the radiation therapy.
To read the PDF file you will need Adobe Reader installed on your computer.