J.Jpn. Surg. Soc.. 83(6): 567-571, 1982

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Original article

STUDIES ON THE PORTAL METABOLISM
I. Effect of Porta Caval Shunt on Ca and Mg Metabolism in Parathyroidectomized Rats

Parathyroidectomy (PTX) in the rat resulted in hypocalsemia and hypomagnesemia and the animal became sick or died in due course. When the portal blood was diverted to the systemic circulation by a porta caval shunt (PCS), the lowered level of these electrolytes returned to normal and the sick animal became healthy again. When PCS was made prior to PTX, the serum electrolytes remained unchanged and the rats stayed healthy.
The study on the transport of Ca and Mg in the intestine revealed that PTX increased the secretion of the electrolytes into the intestine whereas PCS or PCS+PTX enhanced their absorption from the intestine. Possible mechanisms of this unusual finding were discussed.

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