J.Jpn. Surg. Soc.. 83(4): 396-406, 1982
Original article
INFLUENCE OF MASSIVE SMALL BOWEL RESECTION ON THE EXOCRINE AND ENDOCRINE FUNCTIONS OF THE PANCREAS IN DOGS
|
First Department of Surgery, Tottori University School of Medicine (Director : Prof. Shigemasa Koga) Tsutomu Takeuchi |
Maximum bicarbonate concentration increased after 75% distal small bowel resection, but the total volume of pancreatic juice and amylase output did not change after proximal or distal small bowel resection.
Glucose tolerance and insulin release in response to intravenous glucose load were reduced after surgery.
Hyperresponsiveness of pancreatic glucagon to the intravenous arginine infusion, and decreased levels of insulin-glucagon molar ratio were observed after small bowel resection. No change in plasma secretin levels to test meal was noticed.
On the basis of the above, it is reasonable to assume that the influences of reduced gut hormones caused by the massive small bowel resection were greater on the pancreatic endocrine function than on the exocrine function. Neurogenic compensatory response may play an important role on the pancreatic exocrine function after surgery.
To read the PDF file you will need Adobe Reader installed on your computer.