J.Jpn. Surg. Soc.. 83(3): 257-263, 1982
Original article
USEFULNESS OF CALCITONIN FOR TREATMENT OF BONE METASTASES FROM THE BREAST CANCER
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The 1st Department of Surgery, The Shiga University of Medical Sciences, School of Medicine Yoji Shiogai, Masahiro Horisawa, Tohru Tani, Noboru Yamaguchi, Naruo Uehara, Fujio Tsunoda, Toshikazu Hashimoto, Satoshi Etani, Masashi Kodama |
There are many experimental studies about the osteoplastic effects of calcitonin and it has been used for the treatment of such orthopedic diseases as osteoporosis, Paget's diease, polyostotic fibrous dysplasia and so on.
In this paper it is reported that calcitonin was used for 2 cases of bone metastases from the breast cancers and markedly relieved stubborn pain of the metastatic sites. On X-ray examination after administration of calcitonin osteolytic metastases have changed to osteoplastic in one case, and in the other case the remarkable callus formation was recognized at the pathologically fractured lesion. There appeared gradual decrease of pain in accordance with the progression of calcification at the metastatic lesions.
So calcitonin is recommended for the treatment of bone metastases from the breast cancer although it is completely a symptomatic therapy.
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