J.Jpn. Surg. Soc.. 82(12): 1455-1467, 1981
Original article
TIE CLINCAL OBSERVATIONS OF THE PANCREATIC ENZYME LEVEL BEFORE AND AFTER SURGERY
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Second Department of Surgery, Tokyo Medical and Dental University (Director:Prof. Kenichi Asano) Katsuhiro Saito |
1) Hyperamylasemia occurred in 79 of the 132 patients. Of the 79 patients, sixty-three were observed after major abdominal surgery, but 16 were observed after other types of surgery. The findings showed that the setrum amylase level was related to direct or indirect injury to the pancreas during surgery. However, since the origin of amylase is not only the pancreas, but also salivary gland and other organs, the serum amylase level cannot always reflect the pathophysiology of the pancreas after surgery. In order to improve our understanding of the pathophysiology of the pancreas, analysis of the amylase isozyme was also conducted, but it was realized that further study was still necessary.
2) The pancreatic lipase level was also studied in 133 patients. There were 38 patients with hyperlipasemia. Of these 38 patients, 34 were observed after major abdminal surgery, the remaining 4 were observed after other types of surgery. Twenty-nine of the 38 patients with hyperlipasemia had hyperamylasemia, but only 29 of the 79 patients with hyperamylasemia had hyperlipasemia.
From these results, it can be comcluded that serum pancreatic lipase level reflects the pathophysiology of the pancreas more clearly than serum amylase level.
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