J.Jpn. Surg. Soc.. 82(9): 1015-1019, 1981
Report on the annual meeting
METABOLIC STUDY ON ACUTE ARTERIAL OCCLUSION OF THE EXTREMITIES
|
First Department of Surgery, Gifu University School of Medicin Mitsuo Hirose, Koji Matsumoto, Nobuyasu Kano |
Five of them resulted in revascularization syndrome.
Some clinical and experimental studies were done from the metabolic viewpoint to elucidate the characteristics of the revascularization syndrome.
Amino acids, myoglobin, aldolase, CPK and some other enzymes were measured clinically and experimentally.
In patients, potassium, GOT, LDH and CPK were moderately elevated while myoglobin showed remarkable increase and aldolase slight increase. Amino acids showed remarkable increase in 3-methyl histidine and moderate increase in phenylalanine and arginine.
In experimental dogs with their femoral arteries ligated and two thirds of femoral muscles divided, aldolase and myoglobin showed remarkable increase without significant changes in electrolites.
Amino acids showed elevation in urea, taurin, 3-methyl histidine, isoleucine, leucine, glycine, serine, phenylalanine, tyrosine, lysine, asparagine, valine, histidine and arginine.
Measurement of 3-methyl histidine whose normal value in man is trace as well as myoglobin and other enzymes must be of great help in diagnosis of acute arterial occlusion and prediction of its prognosis.
To read the PDF file you will need Adobe Reader installed on your computer.