J.Jpn. Surg. Soc.. 82(6): 647-657, 1981

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Original article

EFFECTIVITY OF DISTAL SPLENORENAL SHUNT ON HEMODYNAMIC CHANGES OF GASTRIC WALL-EXPERIMENTAL STUDY IN ACUTE PORTAL HYPERTENSION

This study was made to evaluate hemodynamic changes of gastric wall after performing distal splenorenal shunt in acute portal hypertension produced by portal stenosis in 11 mongrel dogs comparing 13 control dogs which were treated as above except without shunt. The following results were obtained.
(1) Decrease of gastric wall blood flow was 75.5% in control dogs, whereas it was 22.5% in dogs with shunt, and this difference was significant. (2) Pressure in short gastric vein was elevated up to portal pressure in control dogs, whereas there was essentially no increase of pressure observed in dogs with shunt. (3) Decrease of PtO₂ in gastric wall was significantly greater in control dogs than in dogs with shunt. (4) Histological changes of gastric wall in control dogs were congestion and edema, whereas no changes were observed in dogs with shunt. Thus, distal splenorenal shunt causedl little disturbance in hemodynamics of gastric wall in acute portal hypertension.

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