J.Jpn. Surg. Soc.. 81(12): 1536-1546, 1980

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Original article

FREE WATER CLEARANCE AFTER OPEN HEART SURGERY COMPARATIVE STUDY OF THE CARDIOPULMONARY BYPASS WITH AND WITHOUT DONOR BLOOD

The free water clearance (C_H2O)was measured in 61 cases which underwent open heart surgery. They were divided into two groups, such as 42 cases of cardiopulmonary bypass (CPB) without donor blood and 19 cases with donor blood.
The results were as follows:
1. C_H2O values before CPB were correlative with the daily urine volume. (r=0.65)
2. C_H2O values before CPB were not correlative with the cardiothoracic ratio, pulmonary arterial pressure and pulmonary wedge pressure.
3. Most of the cases of CPB without donor blood revealed a low C_H2O values except 3 cases in which a positive C_H2O value indicated.
4. Most of the cases of CPB with donor blood revealed a low C_H2O values like the cases without donor blood. No case indicated a positive C_H2O value.
5. The pattern of the C_H2O value changes after CPB was classified into 4 types. Types I and II signified a good concentrative capacity in the kidney. Types III and IV signified a poor concentrative capacity in the kidney. 95% of the cases without donor blood and 50% with donor blood were revealed types I and II.
6. CPB without donor blood was the better method for maintaining renal function during and after open heart surgery.

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